Previous findings of sex‐differences in type, location, consequences, and risk factors of running‐related injuries (RRIs) are contradictory. We aim to clarify these potential sex‐differences. This cohort study analyzed prospective RRIs among recreational runners participating in running events (5–42 km) by combining data of two RCTs, including all intervention arms. Participants received a baseline questionnaire at registration and three follow‐up questionnaires (before and up to 1 month after the event) detailing runners characteristics, injury characteristics (location, type [muscle and tendon], joint injury, etc.), and consequences (medication use, pain scores [0–10]). A predetermined injury definition was used to register RRIs. Data analysis was performed using descriptive statistics and univariate and multivariable logistic regression analysis of risk factors for a new RRI (demographics, training characteristics, event distance, and RRI‐history), using separate models per sex. We analyzed 6428 participants with an average follow‐up time of 4.8 months, 82% finished at least one follow‐up questionnaire. During follow‐up, 2133 (33%) participants (33% men, 34% women) suffered one or more RRIs. We found no sex‐differences in injury location and type of injury. Men used less medication (13% vs. 15%, p = 0.01) and had lower pain scores while running (4.2 [SD2.9] vs. 4.5 [SD 2.8], p = 0.04) compared to women. A history of RRIs was associated with a new RRI in both men (OR 1.9 [95% CI: 1.6–2.2]) and women (OR 1.7 [95% CI: 1.4–2.0]). No relevant sex‐differences were found between middle‐aged runners. Our findings do not support accounting for sex‐specific factors, specifically with regard to training characteristics, injury history, or injury consequences, in the development of personalized RRI risk reduction.Trial Registration: The INSPIRE trial (NTR5998) and SPRINT study (NL7694) were prospectively registered in the Dutch Trial Register

中文翻译：

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休闲跑步者特征的性别差异和与新的跑步相关损伤相关的因素


先前发现跑步相关损伤 （RRI） 的类型、位置、后果和危险因素的性别差异是相互矛盾的。我们的目标是澄清这些潜在的性别差异。该队列研究通过结合两项 RCT（包括所有干预组）的数据，分析了参加跑步活动 （5-42 km） 的休闲跑步者的前瞻性 RRI。参与者在注册时收到一份基线问卷和三份随访问卷（活动前和活动后 1 个月），详细说明跑步者的特征、受伤特征（位置、类型 [肌肉和肌腱]、关节损伤等）和后果（药物使用、疼痛评分 [0-10]）。使用预先确定的伤害定义来登记 RRI。使用描述性统计和新 RRI 风险因素（人口统计学、训练特征、事件距离和 RRI 历史）的单变量和多变量 logistic 回归分析进行数据分析，使用每个性别的单独模型。我们分析了 6428 名参与者，平均随访时间为 4.8 个月，82% 完成了至少一份随访问卷。在随访期间，2133 名 （33%） 参与者 （33% 男性，34% 女性） 患有一种或多种 RRI。我们发现受伤部位和受伤类型没有性别差异。与女性相比，男性使用的药物较少 （13% vs. 15%，p = 0.01） 并且跑步时的疼痛评分较低 （4.2 [SD2.9] vs. 4.5 [SD 2.8]，p = 0.04）。男性 （OR 1.9 [95% CI： 1.6–2.2]）和女性 （OR 1.7 [95% CI： 1.4–2.0]） 的 RRI 病史与新的 RRI 相关。在中年跑步者之间没有发现相关的性别差异。 我们的研究结果不支持在开发个性化 RRI 风险降低时考虑性别特异性因素，特别是关于训练特征、受伤史或受伤后果。试验注册：INSPIRE 试验 （NTR5998） 和 SPRINT 研究 （NL7694） 在荷兰试验注册库中前瞻性注册