We report herein a visible-light photoredox-catalyzed 1,4-hydrofluoromethylation of terminal-alkene-derived 1,3-enynes with sodium fluoromethylsulfinate, providing an effective protocol to access a diversity of di- and trisubstituted allenes under mild conditions. The synthetic utility of the present protocol was demonstrated by a large-scale reaction as well as the synthetic derivatization of the allene product.

中文翻译：

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可见光光氧化还原催化的 1,3-烯炔的自由基-极叉 1,4-氢氟甲基化


我们在此报道了可见光光氧化还原催化的末端烯烃衍生的 1,3-烯烃与氟甲基亚磺酸钠的 1,4-氢氟甲基化反应，提供了一种在温和条件下获得多种二取代和三取代烯烃的有效方案。本方案的合成效用通过大规模反应以及丙烯产物的合成衍生化得到证明。