The preparation of binary metal chalcogenides with ideal architectures can effectively enhance the electrocatalytic properties of these materials, as promising glucose sensors. Herein, CoMn-S spheres were synthesized using CoMn-glycerate as the precursor, followed by a sulfidation reaction. First, glycerate spheres were prepared by solvothermal treatment of Co and Mn ions in isopropanol solvent mixed with glycerol. Then, CoMn-glycerate was solvothermally sulfidized using an ion-exchange process to prepare glycerate-assisted CoMn-S spheres with many nanoparticles on their surface which provide abundant electrocatalyst sites. The sensing outcomes revealed that glycerate-assisted CoMn-S spheres have impressive electroanalytical performance with high sensitivities of 5148 and 1928 μA mM⁻¹ cm⁻² in broad measuring ranges of 0.001–0.63 mM and 0.63–2.53 mM, quick response to glucose oxidation (2 s), and a low detection limit of (0.88 μM). Furthermore, the sensor has been successfully employed to measure glucose in human serum, saliva, and beverage samples such as fruit juice, milk, and soft drinks with satisfactory recoveries. The high electrocatalytic activity of the CoMn-S sphere sensor results from the synergy between the components and nanoparticle-assembled microspheres, which creates a high surface area, shortens the charge transfer routes, and improves the electro-conductivity. The performance characteristics of the glycerate-assisted CoMn-S spheres were compared with CoMn-hydroxide needles and CoMn-S sheets. The glycerate-derived design provides an efficient and effective strategy to construct the enzyme-free platforms with high assay capability.

中文翻译：

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甘油酸辅助 CoMn 硫化物，具有受纳米颗粒限制的微球结构，是一种高效的无酶传感器，用于血清、唾液和饮料样品中葡萄糖的安培测量


制备具有理想结构的二元金属硫属化物可以有效增强这些材料的电催化性能，作为有前途的葡萄糖传感器。在此，使用 CoMn-甘油酸盐作为前驱体合成 CoMn-S 球，然后进行硫化反应。首先，通过在异丙醇溶剂中对 Co 和 Mn 离子与甘油混合进行溶剂热处理来制备甘油酸盐球。然后，使用离子交换工艺对 CoMn-甘油酸盐进行溶剂热硫化，以制备甘油酸盐辅助的 CoMn-S 球体，其表面有许多纳米颗粒，可提供丰富的电催化剂位点。传感结果表明，甘油酸辅助 CoMn-S 球体具有令人印象深刻的电分析性能，在 0.001-0.63 mM 和 0.63-2.53 mM 的宽测量范围内具有 5148 和 1928 μA ^{mM-1 cm-2} 的高灵敏度，对葡萄糖氧化的快速响应 （2 s），检测限低 （0.88 μM）。此外，该传感器已成功用于测量人血清、唾液和饮料样品（如果汁、牛奶和软饮料）中的葡萄糖，并取得了令人满意的回收率。CoMn-S 球体传感器的高电催化活性是组件和纳米颗粒组装微球之间的协同作用的结果，从而产生了高表面积，缩短了电荷转移路线，并提高了导电性。将甘油酸辅助 CoMn-S 球的性能特征与 CoMn-氢氧化物针和 CoMn-S 片材进行了比较。甘油酸衍生设计提供了一种高效的策略来构建具有高检测能力的无酶平台。