Background

Air purifiers can enhance indoor air quality and health outcomes, and studies have primarily focused on filters and particulate matter (PM) in households. Photocatalytic oxidation (PCO) is a promising technique for eliminating gaseous pollutants and bioaerosols. However, no field study was conducted in household. Therefore, this study evaluated the effects of the PCO and PCO + filters intervention on indoor air pollutants and cardiopulmonary endpoints in households.

Methods

A randomized, double-blind crossover clinical trial was conducted. Indoor air pollutants, including PM, bioaerosols, and gaseous pollutants and cardiopulmonary endpoints including lung function, fractional exhaled nitric oxide (FeNO), respiratory symptoms, and blood pressure were assessed before and after intervention.

Findings

This was the first study to evaluate the effects of PCO and PCO + filters interventions on indoor air pollutants and cardiopulmonary health in households. Indoor total volatile organic compounds (TVOC) and sulfur dioxides (SO₂) significantly reduced after PCO intervention, however, we also observed the significant reduction in percentage of predicted values of forced vital capacity (FVC%) and forced expiratory volume in 3 s (FEV₃%) and increased in FeNO after 13 days of PCO intervention. The PCO + filters intervention significantly reduced the levels of indoor PM₁, PM_2.5, PM₄, PM₁₀, total suspended particulate matter, ultrafine particles, airborne bacteria, fungi, endotoxin, mites, TVOC, nitrogen dioxide, and SO₂, and marginal reduction in carbon monoxide. However, indoor carbon dioxide significantly increased after PCO/PCO + filters intervention. As for cardiopulmonary health, FVC%, and FEV1% marginally increased 7 days after the PCO + filters intervention.

中文翻译：

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通过光催化氧化和过滤空气净化器改善哮喘患者的室内空气质量和心肺健康

 背景

空气净化器可以提高室内空气质量和健康结果，研究主要集中在家庭中的过滤器和颗粒物 （PM）。光催化氧化 （PCO） 是一种很有前途的消除气态污染物和生物气溶胶的技术。然而，没有在家庭中进行田间研究。因此，本研究评估了 PCO 和 PCO + 过滤器干预对室内空气污染物和家庭心肺终点的影响。

 方法

进行了一项随机、双盲交叉临床试验。在干预前后评估室内空气污染物，包括 PM、生物气溶胶和气态污染物，以及心肺终点，包括肺功能、呼出气一氧化氮 （FeNO） 、呼吸道症状和血压。

 发现

这是第一项评估 PCO 和 PCO + 过滤器干预对室内空气污染物和家庭心肺健康影响的研究。PCO 干预后室内总挥发性有机化合物 （TVOC） 和二氧化硫 （SO₂） 显著降低，然而，我们还观察到用力肺活量 （FVC%） 和 3s 用力呼气容积 （FEV₃%） 预测值的百分比显着降低，并且 FeNO 增加PCO 干预 13 天后。PCO + 过滤器干预显著降低了室内 PM₁、PM_2.5、PM₄、PM₁₀、总悬浮颗粒物、超细颗粒物、空气传播细菌、真菌、内毒素、螨虫、TVOC、二氧化氮和 SO₂ 的水平，并略微降低了一氧化碳。然而，在 PCO/PCO + 过滤器干预后，室内二氧化碳显着增加。至于心肺健康，PCO + 过滤器干预后 7 天 FVC% 和 FEV1% 略有增加。