Catalytic electrochemical asymmetric catalysis starting to emerg as a promising strategy for the synthesis of chiral compounds. Herein, we report an asymmetric electrochemical nickel-catalysed reductive conjugate addition of alkenyl bromides/aryl iodides to α,β-unsaturated ketones in an undivided cell, leading to the addition products with high yields and excellent enantioselectivities (up to 96% yield and 96% ee).

中文翻译：

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α，β-不饱和酮的对映选择性镍催化电化学还原共轭烯基化


催化电化学不对称催化开始成为合成手性化合物的一种有前途的策略。在此，我们报道了烯基溴化物/芳基碘化物与未分割细胞中 α，β-不饱和酮的不对称电化学镍催化还原共轭加成反应，导致加成产物具有高产率和优异的对映选择性（高达 96% 的产率和 96% 的 ee）。