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The Future of Biohybrid Regenerative Bioelectronics
Advanced Materials ( IF 27.4 ) Pub Date : 2024-11-20 , DOI: 10.1002/adma.202408308
Alejandro Carnicer-Lombarte, George G. Malliaras, Damiano G. Barone

Biohybrid regenerative bioelectronics are an emerging technology combining implantable devices with cell transplantation. Once implanted, biohybrid regenerative devices integrate with host tissue. The combination of transplant and device provides an avenue to both replace damaged or dysfunctional tissue, and monitor or control its function with high precision. While early challenges in the fusion of the biological and technological components limited development of biohybrid regenerative technologies, progress in the field has resulted in a rapidly increasing number of applications. In this perspective the great potential of this emerging technology for the delivery of therapy is discussed, including both recent research progress and potential new directions. Then the technology barriers are discussed that will need to be addressed to unlock the full potential of biohybrid regenerative devices.

中文翻译:


生物混合再生生物电子学的未来



生物混合再生生物电子学是一种将植入式设备与细胞移植相结合的新兴技术。植入后,生物混合再生设备与宿主组织整合。移植和装置的结合提供了一种途径,既可以替换受损或功能失调的组织,也可以高精度地监测或控制其功能。虽然生物和技术组件融合的早期挑战限制了生物混合再生技术的发展,但该领域的进步导致应用数量迅速增加。从这个角度来看,讨论了这项新兴技术在提供治疗方面的巨大潜力,包括最近的研究进展和潜在的新方向。然后讨论了需要解决的技术障碍,以释放生物混合再生设备的全部潜力。
更新日期:2024-11-20
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