Space biology and health data are critical for the success of deep space missions and sustainable human presence off-world. At the core of effectively managing biomedical risks is the commitment to open science principles, which ensure that data are findable, accessible, interoperable, reusable, reproducible and maximally open. The 2021 integration of the Ames Life Sciences Data Archive with GeneLab to establish the NASA Open Science Data Repository significantly enhanced access to a wide range of life sciences, biomedical-clinical and mission telemetry data alongside existing ‘omics data from GeneLab. This paper describes the new database, its architecture and new data streams supporting diverse data types and enhancing data submission, retrieval and analysis. Features include the biological data management environment for improved data submission, a new user interface, controlled data access, an enhanced API and comprehensive public visualization tools for environmental telemetry, radiation dosimetry data and ‘omics analyses. By fostering global collaboration through its analysis working groups and training programs, the open science data repository promotes widespread engagement in space biology, ensuring transparency and inclusivity in research. It supports the global scientific community in advancing our understanding of spaceflight's impact on biological systems, ensuring humans will thrive in future deep space missions.

中文翻译：

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NASA 开放科学数据存储库：面向太空生命的开放科学


空间生物学和健康数据对于深空任务的成功和人类在外星的可持续存在至关重要。有效管理生物医学风险的核心是致力于开放科学原则，确保数据可查找、可访问、可互操作、可重用、可重复和最大程度地开放。2021 年将艾姆斯生命科学数据档案与 GeneLab 集成以建立 NASA 开放科学数据存储库，显着增强了对各种生命科学、生物医学临床和任务遥测数据以及来自 GeneLab 的现有组学数据的访问。本白皮书介绍了新数据库、其架构和新数据流，这些数据库支持多种数据类型并增强了数据提交、检索和分析能力。功能包括用于改进数据提交的生物数据管理环境、新的用户界面、受控数据访问、增强的 API 以及用于环境遥测、辐射剂量学数据和组学分析的综合公共可视化工具。通过其分析工作组和培训计划促进全球合作，开放科学数据存储库促进了空间生物学的广泛参与，确保了研究的透明度和包容性。它支持全球科学界推进我们对太空飞行对生物系统影响的理解，确保人类在未来的深空任务中茁壮成长。