Bioactive peptides are polypeptides with specific amino acid sequences that exhibit biological activities and health benefits. Insects have emerged as a sustainable source of proteins in human food and animal feed due to their efficient resource utilization, low environmental footprint, and good nutritional profile. Moreover, insect-derived bioactive peptides (IBPs) offer potential applications in functional foods and pharmaceuticals due to their antioxidant, antimicrobial, antihypertensive, anti-inflammatory, antidiabetic, and anti-obesity activities. In this article, the isolation, purification, and properties of IBPs are reviewed, as well as their potential health benefits, commercial applications, and safety. Despite the growing interest in incorporating IBPs into food products, challenges regarding consumer acceptance, safety, and regulations still persist. Thus, there is a pressing need for further research in this area, as well as clarification of the regulatory framework, before the full potential of insects as a sustainable source of bioactive peptides for human consumption can be realized.

中文翻译：

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昆虫蛋白来源的生物活性肽：制备、生物活性、潜在应用和安全问题


生物活性肽是具有特定氨基酸序列的多肽，具有生物活性和健康益处。昆虫因其高效的资源利用、低环境足迹和良好的营养成分而成为人类食物和动物饲料中蛋白质的可持续来源。此外，昆虫衍生的生物活性肽 （IBP） 因其抗氧化、抗菌、抗高血压、抗炎、抗糖尿病和抗肥胖活性而在功能性食品和药品中具有潜在的应用。本文回顾了 IBP 的分离、纯化和特性，以及它们的潜在健康益处、商业应用和安全性。尽管人们对将 IBP 纳入食品的兴趣日益浓厚，但消费者接受度、安全性和法规方面的挑战仍然存在。因此，在实现昆虫作为人类消费生物活性肽可持续来源的全部潜力之前，迫切需要在这一领域进行进一步研究，并澄清监管框架。