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Endocytic tagging for degradation
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2024-11-19 , DOI: 10.1038/s41551-024-01293-5 Filipe V. Almeida
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2024-11-19 , DOI: 10.1038/s41551-024-01293-5 Filipe V. Almeida
Proteins that tag surface receptors for degradation by triggering their endocytosis can be computationally designed so that they do not compete with native receptor ligands for binding.
中文翻译:
用于降解的内吞标记
通过触发表面受体的内吞作用来标记表面受体进行降解的蛋白质可以通过计算进行设计,使其不会与天然受体配体竞争结合。
更新日期:2024-11-19
中文翻译:
用于降解的内吞标记
通过触发表面受体的内吞作用来标记表面受体进行降解的蛋白质可以通过计算进行设计,使其不会与天然受体配体竞争结合。