Objectives The relationship between nut intake and disability-free survival (healthy lifespan) in later life is unclear. The objective was to evaluate the association between nut intake and disability-free survival in a cohort of adults aged ≥70 years, and whether this varied according to overall diet quality. Methods This prospective cohort study involved 9916 participants from the ASPREE Longitudinal Study of Older Persons. Participants completed a 49-item Food Frequency questionnaire from which frequency of nut intake was obtained and were asked to categories usual intake as no/infrequent [never/rarely, 1–2 times/month], weekly [1–2 times/week, often 3–6 times/week] or daily [every day or several times a day]. The outcome measured was a composite of first-event mortality, onset of dementia, or persistent physical disability. Cox proportional hazards regression models, adjusted for socio-demographic factors, health-related and clinical covariates and overall dietary quality were conducted to examine the association between varying levels of nut intake and disability-free survival. Results Over a mean of 3.9 years of follow-up, the risk of reaching the DFS endpoint were 23% lower (HR 0.77 [0.61–0.98]) for those who consumed nuts daily, when compared to those with no/infrequent nut consumption. Subgroup analysis demonstrated a significant association between daily nut consumption and healthy lifespan among individuals in the second dietary quality tertile (HR 0.71[0.51–0.98]). Conclusion For community-dwelling adults aged 70 years and over with sub-optimal diets, daily nut consumption is associated with the promotion of healthy lifespan (disability-free survival).

中文翻译：

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社区老年人的坚果消费和无残疾生存率：一项前瞻性队列研究


目的 坚果摄入量与晚年无残疾生存率（健康寿命）之间的关系尚不清楚。目的是评估 70 岁成年人队列中坚果摄入量与无残疾生存率之间的关联≥以及这是否根据整体饮食质量而变化。方法 这项前瞻性队列研究涉及来自 ASPREE 老年人纵向研究的 9916 名参与者。参与者完成了一份包含 49 个项目的食物频率问卷，从中获得了坚果摄入量的频率，并被要求将通常摄入量分为无/不频繁 [从不/很少，1-2 次/月]、每周 [1-2 次/周，通常 3-6 次/周] 或每天 [每天或每天几次]。测量的结局是首次事件死亡率、痴呆发作或持续性身体残疾的综合结果。进行了针对社会人口学因素、健康相关和临床协变量以及整体饮食质量进行调整的 Cox 比例风险回归模型，以检查不同水平的坚果摄入量与无残疾生存率之间的关联。结果在平均 3.9 年的随访中，与不/不经常食用坚果的人相比，每天食用坚果的人达到 DFS 终点的风险降低了 23% （HR 0.77 [0.61–0.98]）。亚组分析表明，在第二饮食质量三分位数 （HR 0.71[0.51–0.98]） 中，个体的每日坚果消费与健康寿命之间存在显著关联。结论 对于 70 岁及以上饮食不佳的社区居民，每日食用坚果与促进健康寿命（无残疾生存）有关。