We developed a methodology to study the extraction of high-value solutes directly from suspensions of finely disrupted substrates. For that, we modelled the high-pressure phase equilibrium for the ternary (CO2 + ethanol + water) system using experimental literature data. Different compositions of hydroethanolic mixture and CO2 were loaded into an extraction vessel set at 30–35 MPa and 40–50 °C during static extraction, and a gaseous mixture with the composition of the CO2-rich gaseous phase in the extraction vessel was continuously fed during dynamic extraction. Losses of the fed hydroethanolic mixture occurred mainly during dynamic extraction (10–30 wt%) and were properly distributed to account for actual flows and compositions of experimental streams. Mostly, equilibrium conditions were reached following about 1 h of the 2-h dynamic extraction, and good reproducibility was achieved. In conclusion, equilibrium is reached in which two phases coexist in equilibrium within the extraction vessel: a water-rich liquid phase and a CO2-rich gaseous phase.

中文翻译：

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一种验证使用水乙醇混合物作为悬浮液超临界 CO2 萃取悬浮剂的悬浮介质/改性剂的实验方法


我们开发了一种方法来研究直接从精细破碎底物的悬浮液中提取高价值溶质。为此，我们使用实验文献数据模拟了三元（CO2 + 乙醇 + 水）系统的高压相平衡。在静态萃取过程中，将不同成分的水乙醇混合物和 CO2 装入设置为 30–35 MPa 和 40–50 °C 的萃取容器中，并在动态萃取过程中连续进料萃取容器中具有富含 CO2 气相成分的气态混合物。补料氢乙醇混合物的损失主要发生在动态萃取期间 （10-30 wt%），并且根据实验流的实际流量和成分进行适当分配。大多数情况下，在 2 小时动态提取约 1 小时后达到平衡条件，并且获得了良好的重现性。总之，达到平衡，其中两个相在提取容器内平衡共存：富水液相和富含 CO2 的气相。