The step-economical synthesis of pyrrole derivatives has posed a challenge in the field of N-heterocyclic chemistry. A novel photocascade catalytic radical S_N2′-type reaction/radical addition/annulation sequence of MBH acetates provides a straightforward route to pyrrole derivatives by forming new C–C, C–N, and C═C bonds in one pot, using N-arylglycines as the α-arylaminomethyl radical precursors for double insertion.

中文翻译：

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一锅法光级联催化：获得来自 N-芳基甘氨酸和 Morita-Baylis-Hillman （MBH） 乙酸盐的吡咯衍生物


吡咯衍生物的逐步经济合成在 N-杂环化学领域提出了挑战。MBH 乙酸盐的新型光级联催化自由基 S_N2′ 型反应/自由基加成/环化序列通过在一罐中形成新的 C-C、C-N 和 C═C 键，使用 N-芳基甘氨酸作为 α-芳基甲基自由基前体进行双重插入，为吡咯衍生物提供了一条直接的途径。