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Catalysis-enabled amine sorting
Nature Chemistry ( IF 19.2 ) Pub Date : 2024-11-18 , DOI: 10.1038/s41557-024-01676-w
Steven J. Malcolmson

Multicomponent couplings offer powerful approaches for rapidly increasing molecular complexity, but typically require functionally distinct reagents. Now, through dynamic combinatorial chemistry, structurally similar amino groups can be efficiently differentiated, enabling the enantioselective aminomethylamination of dienes to prepare 1,3-diamines.

中文翻译:


催化胺分选



多组分偶联为快速增加分子复杂性提供了强大的方法,但通常需要功能不同的试剂。现在,通过动态组合化学,可以有效地区分结构相似的氨基,使二烯的对映选择性氨基甲胺化能够制备 1,3-二胺。
更新日期:2024-11-18
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