The purpose of the current study was twofold. First, to determine the intraindividual variability of sweat rate per gland for a given skin location during exercise in the heat. Second, to determine the relative importance of intrinsic vs. extrinsic factors as the source of the intraindividual variability in the sweat rate per gland. Sweat rate of individual eccrine glands on the forearm was measured following pilocarpine iontophoresis and during exercise in the heat. In five participants during exercise in the heat, the measured sweat rate for individual forearm eccrine glands (n = 500) ranged from 0.5 nL/gland/min to 16 nL/gland/min, or over a 30-fold difference. The mean (SD) intraindividual coefficient of variation in sweat rate per gland was 36 (5)% and 49 (10)% (p = 0.008) following pilocarpine iontophoresis and during exercise in the heat, respectively. Such results suggest that intrinsic factors (i.e., sweat gland size and cholinergic sensitivity) contribute approximately three times more than extrinsic factors (i.e., sweat gland nerve fiber density and threshold amplitude) towards explaining the large intra-person variability in sweat rate per gland seen during exercise in the heat.

中文翻译：

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内在与外在对个体小汗腺个体内出汗率变化的贡献


本研究的目的有两个。首先，确定在高温下运动期间给定皮肤位置每个腺体的出汗率的个体内变异性。其次，确定内在因素与外在因素作为每个腺体出汗率个体内变化来源的相对重要性。在毛果芸香碱离子电渗疗法后和高温运动期间测量前臂上单个小汗腺的出汗率。在 5 名参与者在高温下运动时，测得的单个前臂小汗腺 （n = 500） 的出汗率范围为 0.5 nL/腺体/min 至 16 nL/腺体/min，或相差 30 倍以上。毛果芸香碱离子电渗疗法后和高温运动期间每个腺体出汗率的平均 （SD） 个体内变异系数分别为 36 （5）% 和 49 （10）% （p = 0.008）。这些结果表明，内在因素（即汗腺大小和胆碱能敏感性）在解释在高温下运动时每个腺体出汗率的巨大人内变化性方面，贡献大约是外在因素（即汗腺神经纤维密度和阈值振幅）的三倍。