Molecular classification of upper tract urothelial carcinoma (UTUC) can provide insight into divergent clinical outcomes and provide a biological rationale for clinical decision-making. As such, we performed multi-omic analysis of UTUC tumors to identify molecular features associated with disease recurrence and response to immune checkpoint blockade (ICB).

中文翻译：

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分子异质性和免疫浸润驱动上尿路尿路上皮癌的临床结局


上尿路尿路上皮癌 （UTUC） 的分子分类可以深入了解不同的临床结果，并为临床决策提供生物学依据。因此，我们对 UTUC 肿瘤进行了多组学分析，以确定与疾病复发和免疫检查点阻断 （ICB） 反应相关的分子特征。