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Recent Advances in Polysaccharides Derived from the Genus Panax: Preparation Strategies, Structural Profiles, Functional Properties and Structure–Activity Relationships
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2024-11-15 , DOI: 10.1021/acs.jafc.4c07918
Yingxuan Bu, Yupeng Liu, Lingyan Zhu, Xiaona Gan, Shenggui Jiang, Xiaoyu Zhang, Munisa Dilixiati, Muwei Bai, Jiani Zeng, Songshan Shi, Tingzhao Li, Bo Li, Shunchun Wang, Huijun Wang

Plants from the Panax genus have significant medicinal and nutritional benefits. Many Panax species are traditionally used in Chinese medicine and have gained popularity as food and health products because of their tonic effects and high safety. Their key bioactive components include polysaccharides, which are hydrophilic biomolecules that have demonstrated significant potential in the food and pharmaceutical industries because of their multiple health-promoting qualities, such as immunomodulatory, antitumor, antiaging, blood glucose and blood lipid regulation, antiviral, hepatoprotective, and gastrointestinal protective properties. Additionally, polysaccharides are abundant in health products made from the genus Panax, such as energy drinks and herbal teas. However, compared with more extensively studied components, such as ginsenosides and saponins, polysaccharides from the genus Panax (GPPs) have been the subject of relatively limited research. This review provides a comprehensive overview of the extraction and purification technology, structural characteristics, biological activities, applications, and structure–activity relationships of GPPs. Ultimately, this information establishes a theoretical foundation for the further development and application of GPPs in nutrition and medicine.

中文翻译:


人多糖属多糖的最新进展:制备策略、结构特征、功能特性和构效关系



Panax 属植物具有显着的药用和营养价值。许多 Panax 物种传统上用于中药,并因其滋补作用和高安全性而作为食品和保健品而广受欢迎。它们的关键生物活性成分包括多糖,多糖是一种亲水性生物分子,由于其多种促进健康的品质,如免疫调节、抗肿瘤、抗衰老、血糖和血脂调节、抗病毒、保肝和胃肠道保护特性,在食品和制药工业中显示出巨大的潜力。此外,多糖在参属制成的保健品中含量丰富,例如能量饮料和凉茶。然而,与人参皂甙和皂苷等更广泛研究的成分相比,人参属 (GPP) 的多糖一直是相对有限的研究对象。本文对 GPPs 的提取纯化技术、结构特征、生物活性、应用和构效关系进行了全面概述。最终,这些信息为 GPPs 在营养和医学领域的进一步发展和应用奠定了理论基础。
更新日期:2024-11-16
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