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Modeling the epidemiologic impact of age-targeted vaccination for drug-resistant tuberculosis
Drug Resistance Updates ( IF 15.8 ) Pub Date : 2024-11-13 , DOI: 10.1016/j.drup.2024.101172 Pei-Yao Zhai, Zhi-Xian Chen, Ting Jiang, Jian Feng, Bin Zhang, Xiao Zang, Yan-Lin Zhao, Gang Qin
Drug Resistance Updates ( IF 15.8 ) Pub Date : 2024-11-13 , DOI: 10.1016/j.drup.2024.101172 Pei-Yao Zhai, Zhi-Xian Chen, Ting Jiang, Jian Feng, Bin Zhang, Xiao Zang, Yan-Lin Zhao, Gang Qin
This study used a calibrated mathematical model to evaluate age-specific tuberculosis (TB) vaccination strategies, for drug-resistant (DR)-TB management in China. Prioritizing elderly vaccination significantly reduced multidrug-resistant or rifampicin-resistant TB incidence and mortality, while avoiding the need for second-line treatment, offering a promising approach to mitigate DR-TB burden by 2050.
更新日期：2024-11-13
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