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Decision-Making Approach to the Treatment of Young and Low-Risk Patients With Aortic Stenosis.
JACC: Cardiovascular Interventions ( IF 11.7 ) Pub Date : 2024-11-11 , DOI: 10.1016/j.jcin.2024.08.032
Tanush Gupta,S Chris Malaisrie,Wayne Batchelor,Konstantinos Dean Boudoulas,Laura Davidson,Uzoma N Ibebuogu,Jacques Kpodonu,Ramesh Singh,Ibrahim Sultan,Misty Theriot,Michael J Reardon,Martin B Leon,Kendra J Grubb,

Over a decade of randomized controlled trial data demonstrate excellent outcomes with transcatheter aortic valve replacement or surgical aortic valve replacement for patients with symptomatic severe aortic stenosis regardless of surgical risk. The 2020 American College of Cardiology/American Heart Association guidelines recommend both options for low-risk AS patients aged 65 to 80 years. However, the fastest growing population of patients receiving transcatheter aortic valve replacement in the United States is <65 years old, with little data to support the practice. The American College of Cardiology's Cardiac Surgery Team Section Leadership and Interventional Cardiology Councils, a multidisciplinary collaboration of cardiologists and cardiac surgeons, sought to summarize the relevant data into a decision-making tool for heart valve teams. A literature review was completed, and guidelines, randomized controlled trials, and large observational studies were summarized into a pragmatic decision-making approach to treating young and low-risk patients with AS.

中文翻译:


治疗年轻和低风险主动脉瓣狭窄患者的决策方法。



十多年的随机对照试验数据表明,经导管主动脉瓣置换术或外科主动脉瓣置换术对有症状的严重主动脉瓣狭窄患者有很好的结果,无论手术风险如何。2020 年美国心脏病学会/美国心脏协会指南推荐了 65-80 岁的低风险 AS 患者这两种选择。然而,在美国接受经导管主动脉瓣置换术的患者群体中增长最快的是 <65 岁,几乎没有数据支持这种做法。美国心脏病学会 (American College of Cardiology) 的心脏外科团队领导和介入心脏病学委员会 (Interventional Cardiology Councils) 是心脏病专家和心脏外科医生的多学科合作组织,旨在将相关数据汇总为心脏瓣膜团队的决策工具。完成了文献综述,并将指南、随机对照试验和大型观察性研究总结为治疗年轻和低风险 AS 患者的实用决策方法。
更新日期:2024-11-11
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