Noncanonical amino acids (ncAAs) are synthetic building blocks that, when incorporated into proteins, confer novel functions and enable precise control over biological processes. These small yet powerful tools offer unprecedented opportunities to investigate and manipulate various complex life forms. In particular, ncAA incorporation technology has garnered significant attention in the study of animals and their constituent cells, which serve as invaluable model organisms for gaining insights into human physiology, genetics, and diseases. This review will provide a comprehensive discussion on the applications of ncAA incorporation technology in animals and animal cells, covering past achievements, current developments, and future perspectives.

中文翻译：

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动物和动物细胞中的非经典氨基酸掺入


非经典氨基酸 （ncAA） 是合成的构建单元，当掺入蛋白质中时，可赋予新功能并能够精确控制生物过程。这些小而强大的工具为研究和操纵各种复杂的生命形式提供了前所未有的机会。特别是，ncAA 掺入技术在动物及其组成细胞的研究中引起了极大的关注，这些细胞是深入了解人类生理学、遗传学和疾病的宝贵模式生物。本文将全面讨论 ncAA 掺入技术在动物和动物细胞中的应用，涵盖过去的成就、当前的发展和未来的展望。