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Brain-Charting Autism and Attention-Deficit/Hyperactivity Disorder Reveals Distinct and Overlapping Neurobiology
Biological Psychiatry ( IF 9.6 ) Pub Date : 2024-08-14 , DOI: 10.1016/j.biopsych.2024.07.024
Saashi A. Bedford, Meng-Chuan Lai, Michael V. Lombardo, Bhismadev Chakrabarti, Amber Ruigrok, John Suckling, Evdokia Anagnostou, Jason P. Lerch, Margot Taylor, Rob Nicolson, Georgiades Stelios, Jennifer Crosbie, Russell Schachar, Elizabeth Kelley, Jessica Jones, Paul D. Arnold, Eric Courchesne, Karen Pierce, Lisa T. Eyler, Kathleen Campbell, Cynthia Carter Barnes, Jakob Seidlitz, Aaron F. Alexander-Bloch, Edward T. Bullmore, Simon Baron-Cohen, Richard A.I. Bethlehem, MRC AIMS Consortium, Anthony J. Bailey, Simon Baron-Cohen, Patrick F. Bolton, Edward T. Bullmore, Sarah Carrington, Marco Catani, Bhismadev Chakrabarti, Michael C. Craig, Eileen M. Daly, Sean C.L. Deoni, Christine Ecker, Francesca Happé, Julian Henty, Peter Jezzard, Patrick Johnston, Derek K. Jones, Meng-Chuan Lai, Michael V. Lombardo, Anya Madden, Diane Mullins, Clodagh M. Murphy, Declan G.M. Murphy, Greg Pasco, Amber N.V. Ruigrok, Susan A. Sadek, Debbie Spain, Rose Stewart, John Suckling, Sally J. Wheelwright, Steven C. Williams, Lifespan Brain Chart Consortium

Autism and attention-deficit/hyperactivity disorder (ADHD) are heterogeneous neurodevelopmental conditions with complex underlying neurobiology that is still poorly understood. Despite overlapping presentation and sex-biased prevalence, autism and ADHD are rarely studied together and sex differences are often overlooked. Population modeling, often referred to as normative modeling, provides a unified framework for studying age-specific and sex-specific divergences in brain development.

中文翻译:


脑图自闭症和注意力缺陷/多动障碍揭示了不同且重叠的神经生物学



自闭症和注意力缺陷/多动障碍 (ADHD) 是异质性神经发育疾病,具有复杂的潜在神经生物学,但仍然知之甚少。尽管表现重叠且存在性别偏见,但自闭症和 ADHD 很少一起研究,性别差异经常被忽视。群体建模,通常称为规范建模,为研究大脑发育中的年龄特异性和性别特异性差异提供了一个统一的框架。
更新日期:2024-08-14
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