Evidence shows that RNA trafficking is a key communication mechanism across kingdoms and species, but how RNAs are secreted and trafficked and how they function within the recipient organisms remain unclear. Here, we discuss how understanding inter-organismal RNA communication can assist in disease management in both agriculture and medicine. Cross-species host–pathogen or mutualistic RNA communication, especially through extracellular vesicles, can have important applications, including gene silencing in agriculture and RNA-based therapeutics.

中文翻译：

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生物体之间的 RNA 通讯激发了创新的环保疾病控制策略


有证据表明，RNA 运输是跨界和物种的关键通信机制，但 RNA 是如何分泌和运输的，以及它们在受体生物体内如何运作仍不清楚。在这里，我们讨论了了解生物体间 RNA 通讯如何帮助农业和医学中的疾病管理。跨物种宿主-病原体或共生 RNA 通讯，尤其是通过细胞外囊泡，可以有重要的应用，包括农业中的基因沉默和基于 RNA 的治疗。