The effort to eradicate Dracunculus medinensis, the etiologic agent of dracunculiasis, or Guinea worm disease, began at CDC in 1980. In 1986, with an estimated 3.5 million global cases in 20 African and Asian countries, the World Health Assembly called for dracunculiasis elimination. The Guinea Worm Eradication Program (GWEP) was established to help countries with endemic dracunculiasis reach this goal. GWEP is led by The Carter Center and supported by partners, including the countries with endemic disease, CDC, UNICEF, and the World Health Organization. Since 2012, infections in dogs, cats, and baboons have posed a new challenge for GWEP, as have ongoing civil unrest and insecurity in some areas. As of June 2024, dracunculiasis remained endemic in five countries (Angola, Chad, Ethiopia, Mali, and South Sudan). Fourteen human cases and 886 animal infections occurred, including 407 dogs in Chad and 248 dogs in Cameroon, reported in 2023, and three human cases and 297 animal infections reported during January-June 2024. Animal infections, primarily in dogs in Cameroon and Chad, and impeded access due to civil unrest and insecurity in Mali, threaten the near-term possibility of global eradication. Nevertheless, countries appear poised to reach zero cases.

中文翻译：

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全球根除麦地那龙线虫病（麦地那龙线虫病）的进展，2023 年 1 月至 2024 年 6 月。


根除麦地那龙线虫病（麦地那龙线虫病或麦地那龙线虫病的病原体）的努力始于 1980 年。1986 年，全球 20 个非洲和亚洲国家估计有 350 万例病例，世界卫生大会呼吁消除麦地那龙线虫病。麦地那龙线虫根除计划 （GWEP） 的建立是为了帮助麦地那龙线虫病流行国家实现这一目标。GWEP 由卡特中心领导，并得到合作伙伴的支持，包括地方病国家、CDC、联合国儿童基金会和世界卫生组织。自 2012 年以来，狗、猫和狒狒的感染给 GWEP 带来了新的挑战，一些地区持续的内乱和不安全也带来了挑战。截至 2024 年 6 月，麦地那龙线虫病仍然在五个国家（安哥拉、乍得、埃塞俄比亚、马里和南苏丹）流行。2023 年报告了 14 例人类病例和 886 例动物感染，包括乍得的 407 例狗和喀麦隆的 248 只狗，以及 2024 年 1 月至 6 月期间报告的 3 例人类病例和 297 例动物感染。动物感染，主要是喀麦隆和乍得的狗，以及马里由于内乱和不安全而阻碍进入，威胁到全球消灭动物的短期可能性。尽管如此，各国似乎已准备好实现零病例。