Children develop rapidly in the preschool period, making accurate appraisals of mental health (MH) difficult. The preschool years are a key period for early identification of MH concerns and could benefit from multi-informant, universal MH screening (UMHS). This systematic review aimed to identify multi-informant UMHS measures for preschool-aged children, and to examine their clinical utility, effectiveness, and acceptability. Studies reporting the predictive and incremental validity, effectiveness or acceptability of parent and educator-report UMHS measures for children aged 3–5 years were identified through CINAHL, Embase, ERIC, Medline, PsycINFO, Scopus and Web of Science. Studies were excluded if screening was not the primary focus, not universal, single informant, or primarily focussed on Autism Spectrum Disorder. A total of 11 studies using 10 measures was identified. Ten studies screened for broad MH difficulties. Three educator-report and one parent- and educator-report measures had acceptable predictive validity. One study reporting incremental validity found that adding educator-report to parent ratings significantly improved the identification of MH concerns. No studies reported on effectiveness. Three studies that explored acceptability reported strong support for either UMHS in general or specific measures. There are promising results that UMHS can accurately identify child MH concerns in the preschool period using parent and educator reports. However, with few of the examined measures reaching the benchmark standards for predictive validity and only one study examining incremental validity, further research is needed to establish clinical utility. UMHS with preschool populations appears to be acceptable; future studies should further examine multi-informant screening in preschool populations. This systematic review was registered with the International Prospective Register of Systematic Reviews (PROSPERO; https://www.crd.york.ac.uk/prospero; registration number: CRD 42022383426).

儿童在学龄前阶段发育迅速，因此难以准确评估心理健康 （MH）。学龄前时期是早期识别 MH 问题的关键时期，可能受益于多线人、通用 MH 筛查 （UMHS）。本系统评价旨在确定针对学龄前儿童的多信息提供者 UMHS 措施，并检查其临床效用、有效性和可接受性。通过 CINAHL、Embase、ERIC、Medline、PsycINFO、Scopus 和 Web of Science 确定了报告家长和教育者报告 UMHS 措施对 3-5 岁儿童的预测和增量效度、有效性或可接受性的研究。如果筛查不是主要重点、不是普遍的、单一的知情者或主要关注自闭症谱系障碍，则研究被排除在外。共确定了 11 项研究，使用 10 项措施。10项研究筛选了广泛的MH困难。3 项教育者报告和 1 项家长和教育者报告测量具有可接受的预测效度。一项报告增量效度的研究发现，在家长评分中增加教育者报告可显著改善对 MH 问题的识别。没有研究报告有效性。三项探讨可接受性的研究报告了对 UMHS 的一般或特定措施的强烈支持。有可喜的结果表明，UMHS 可以使用家长和教育工作者报告准确识别学龄前儿童 MH 问题。然而，由于很少有检查的措施达到预测效度的基准标准，并且只有一项研究检查了增量效度，因此需要进一步的研究来确定临床效用。 学龄前人群的 UMHS 似乎是可以接受的;未来的研究应进一步检查学龄前人群的多线人筛查。本系统综述已在国际系统综述前瞻性注册库（International Prospective Register of Systematic Reviews， PROSPERO;https://www.crd.york.ac.uk/prospero;注册号：CRD 42022383426）注册。