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Metabolism, mitochondria and metastasis in kidney cancer
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2024-11-13 , DOI: 10.1038/s41585-024-00968-7
Louise Lloyd

A study published in Nature investigating tumour metabolism in kidney cancers provides insight into the influence of mitochondria and cellular metabolism on metastasis in this disease.

In this study, a 13C-labelled nutrient, [U-13C]glucose, was administered through a peripheral intravenous line to patients with varying subtypes of renal cell carcinoma (RCC) undergoing partial or radical nephrectomy during their surgery. Overall, 59 patients, 37 of whom had clear cell RCC (ccRCC), were included.



中文翻译:


肾癌的代谢、线粒体和转移



发表在《自然》杂志上的一项研究调查了肾癌中的肿瘤代谢,深入了解了线粒体和细胞代谢对这种疾病转移的影响。


在这项研究中,通过外周静脉导管将 13C 标记的营养素 [U-13C] 葡萄糖给药给在手术期间接受部分或根治性肾切除术的不同肾细胞癌 (RCC) 亚型患者。共纳入 59 例患者,其中 37 例患有透明细胞 RCC (ccRCC)。

更新日期:2024-11-14
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