MarkerDB (https://markerdb.ca) has become a leading resource for comprehensive information on molecular biomarkers. Over the past 3 years, the database has evolved significantly, reflecting the dynamic landscape of biomarker research and increasing demands from its user community. This year’s update, which is called MarkerDB 2.0, introduces key improvements to enhance the database’s usability, consistency and the range of biomarkers covered. These improvements include (i) the addition of thousands of new biomarkers and associated health conditions, (ii) the inclusion of many new biomarker types and categories, (iii) upgraded searches and data filtering functionalities, (iv) new features for exploring and understanding biomarker panels and (v) significantly expanded and improved descriptions. These upgrades, along with numerous minor improvements in content, interface, layout and overall website performance, have greatly enhanced MarkerDB’s usability and capacity to facilitate biomarker interpretation across various research domains. MarkerDB remains committed to providing a free, publicly accessible platform for consolidated information on a wide range of molecular (protein, genetic, chromosomal and chemical/small molecule) biomarkers, covering diagnostic, prognostic, risk, monitoring, safety and response-related biomarkers. We are confident that these upgrades and updates will improve MarkerDB’s user friendliness, increase its utility and greatly expand its potential applications to many other areas of clinical medicine and biomedical research.

中文翻译：

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MarkerDB 2.0：面向 2025 年的综合分子生物标志物数据库


MarkerDB （https://markerdb.ca） 已成为分子生物标志物全面信息的领先资源。在过去的 3 年里，该数据库发生了重大变化，反映了生物标志物研究的动态格局和用户社区不断增长的需求。今年的更新称为 MarkerDB 2.0，引入了关键改进，以增强数据库的可用性、一致性和涵盖的生物标志物范围。这些改进包括 （i） 增加了数千种新的生物标志物和相关健康状况，（ii） 增加了许多新的生物标志物类型和类别，（iii） 升级了搜索和数据过滤功能，（iv） 用于探索和理解生物标志物面板的新功能，以及 （v） 显着扩展和改进描述。这些升级，以及内容、界面、布局和整体网站性能方面的许多细微改进，极大地增强了 MarkerDB 的可用性和能力，以促进各种研究领域的生物标志物解释。MarkerDB 仍然致力于提供一个免费的、可公开访问的平台，以整合各种分子（蛋白质、遗传、染色体和化学/小分子）生物标志物的信息，涵盖诊断、预后、风险、监测、安全和反应相关的生物标志物。我们相信，这些升级和更新将提高 MarkerDB 的用户友好性，增加其实用性，并大大扩展其潜在应用到临床医学和生物医学研究的许多其他领域。