A recent study published in Cell shows the widely known and used antidiabetic drug metformin, has geroprotective benefits in non-human male primates.¹ Metformin is a derivative of biguanide, synthesized in the 1920s and quickly became the first line off-label treatment for type 2 diabetes due to its efficacy in lowering plasma glucose levels.

中文翻译：

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二甲双胍：减慢衰老时钟的生物标志物

最近发表在《细胞》杂志上的一项研究表明，广为人知和使用的抗糖尿病药物二甲双胍对非人类雄性灵长类动物具有老年保护作用。¹ 二甲双胍是双胍的衍生物，于 1920 年代合成，由于其降低血糖水平的功效，迅速成为 2 型糖尿病的一线标签外治疗。