Fast and accurate assessment of skin mechanics holds great promise in diagnosing various epidermal diseases, yet substantial challenges remain in developing simple and wearable strategies for continuous monitoring. Here, we present a design concept, named active near-infrared spectroscopy patch (ANIRP) for continuously mapping skin mechanics. ANIRP addresses these challenges by integrating near-infrared (NIR) sensing with mechanical actuators, enabling rapid measurement (<1 s) of Young’s modulus, high spatial sensing density (~1 cm 2 ), and high spatial sensitivity (<1 mm). Unlike conventional electromechanical sensors, NIR sensors precisely capture vibrational frequencies propagated from the actuators without needing ultraclose contact, enhancing wearing comfort. Demonstrated examples include ANIRPs for comprehensively moduli mapping of artificial tissues with varied mechanical properties emulating tumorous fibrosis. On-body validation of the ANIRP across skin locations confirms its practical utility for clinical monitoring of epidermal mechanics, promising considerable advancements in real-time, noninvasive skin diagnostics and continuous health monitoring.

中文翻译：

---

支持近红外光谱的机电系统，用于生物力学的快速标测和皮下诊断


快速准确地评估皮肤力学在诊断各种表皮疾病方面具有很大的前景，但在开发简单且可穿戴的连续监测策略方面仍然存在重大挑战。在这里，我们提出了一种设计概念，称为主动近红外光谱贴片 （ANIRP），用于连续映射皮肤力学。ANIRP 通过将近红外 （NIR） 传感与机械致动器集成来应对这些挑战，从而能够快速测量 （<1 s） 杨氏模量、高空间传感密度 （~1 cm 2 ） 和高空间灵敏度 （<1 mm）。与传统的机电传感器不同，NIR 传感器无需超近距离接触即可精确捕获从执行器传播的振动频率，从而提高佩戴舒适度。演示的示例包括 ANIRPs，用于对模拟肿瘤纤维化的具有不同机械特性的人工组织进行全面模数映射。ANIRP 在皮肤部位的本体验证证实了其在临床监测表皮力学方面的实际效用，有望在实时、无创皮肤诊断和持续健康监测方面取得重大进步。