1,1-Diethoxybutane (DEB) was synthesized in a Simulated Moving Bed Reactor (SMBR) consisting of eight columns packed with the commercial resin Amberlyst15. The True Moving Bed Reactor (TMBR) model was used to model the reaction/separation process and to select the best experimental conditions for the process. The experiences of two types of assays, named runs 1 and 2, were analyzed with preset conditions as detailed in the article. The best conversion obtained was 94% for run 2 but with low raffinate purity (66%) and productivity (1.8 kg_DEBL^–1day^–1). On the other hand, the best raffinate productivity was 3.7 kg_DEBL^–1day^–1 for run 1, with a lower conversion (88%) and purity (60%). These results show that the SMBR pilot unit has a great potential to be competitive and efficient compared to other traditional processes for the synthesis of 1,1-diethoxybutane, which can be extensible to other acetals. In addition to highlighting that the process proves to be environmentally friendly, it is suggested that improvement in performance would be achieved by working with full resin regeneration in section 1 and full desorbent cleaning in section 4. These recommendations would also improve the quantitative representation of the model, although qualitatively the modeling is considered acceptable.

中文翻译：

---

模拟移动床反应器中试装置中 1,1-二乙氧基丁烷合成过程的操作和建模


1,1-二乙氧基丁烷 （DEB） 是在模拟移动床反应器 （SMBR） 中合成的，该反应器由八根填充有商业填料 Amberlyst15 的塔组成。真实移动床反应器 （TMBR） 模型用于模拟反应/分离过程并为该过程选择最佳实验条件。使用文章中详述的预设条件分析了两种类型的分析方法（称为运行 1 和 2）的经验。第 2 次运行获得的最佳转化率为 94%，但残余液纯度 （66%） 和生产率 （1.8 kg_DEBL^–1day^–1） 较低。另一方面，第 1 次运行的最佳抽余油生产率为 3.7 kg_DEBL^–1day^–1，转化率 （88%） 和纯度 （60%）较低。这些结果表明，与其他传统工艺合成 1,1-二乙氧基丁烷相比，SMBR 中试装置具有很大的竞争力和效率潜力，1,1-二乙氧基丁烷可以扩展到其他缩醛。除了强调该工艺被证明是环保的外，还建议通过在第 1 部分使用完全树脂再生和在第 4 部分使用完全脱附剂清洁来提高性能。这些建议还将改进模型的定量表示，尽管从质量上讲，该模型被认为是可以接受的。