Bacteriophages have evolved numerous mechanisms to evade targeting by CRISPR-Cas defense systems. However, the evolutionary origin of these so-called “anti-CRISPRs” remains poorly understood. In a recent issue of Nature, Katz et al.¹ provide evidence that some anti-CRISPRs were derived from genes of the CRISPR-Cas systems themselves.

中文翻译：

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如果你打不过他们，那就加入他们：来源于 CRISPR 相关基因的抗 CRISPR 蛋白


噬菌体已经进化出许多机制来逃避 CRISPR-Cas 防御系统的靶向。然而，这些所谓的“抗 CRISPR”的进化起源仍然知之甚少。在最近一期的 Nature 杂志上，Katz 等人1 提供了证据，证明一些抗 CRISPR 抗体来源于 CRISPR-Cas 系统本身的基因。