Tuberculosis remains a formidable global health challenge, with Mycobacterium tuberculosis responsible for millions of cases and deaths annually. In this issue of Cell Host & Microbe, Worakitchanon et al. present a method to identify structural variants in Mtb and explore associations with bacterial phenotypes such as virulence and antibiotic resistance.

中文翻译：

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不可磨灭的影响：结构变异如何驱动毒力和耐药性


结核病仍然是一项艰巨的全球健康挑战，结核分枝杆菌每年造成数百万例病例和死亡。在本期的Cell Host & Microbe中，Worakitchanon等人提出了一种识别Mtb结构变异的方法，并探索与细菌表型如毒力和抗生素耐药性的关联。