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mRNA vaccines: A promising platform for safer, more effective next-generation Orthopoxvirus immunization
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2024-11-13 , DOI: 10.1016/j.chom.2024.10.014
Xiaonan Han, Qingrui Huang, Jinghua Yan

In recent work, Mucker et al.1 demonstrated that mRNA-1769 outperforms modified vaccinia Ankara (MVA), which has been deployed against recent mpox virus (MPXV) outbreaks, in reducing clinical symptoms and controlling viral replication, highlighting its potential as a scalable, safe, and effective next-generation platform for orthopoxvirus vaccination.

中文翻译:


mRNA 疫苗:更安全、更有效的下一代正痘病毒免疫的有前途的平台



在最近的研究中,Mucker 等人1 证明,mRNA-1769 在减少临床症状和控制病毒复制方面优于改良的安卡拉痘苗 (MVA),后者已被用于对抗最近的 mpox 病毒 (MPXV) 爆发,突出了其作为可扩展、安全和有效的下一代正痘病毒疫苗接种平台的潜力。
更新日期:2024-11-13
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