Plasmid conjugation has been extensively studied over the past decades. Yet, in most plasmids, the minimal region required for conjugation (the origin of transfer (oriT) sequence) is unknown. The characterization of known oriTs enabled the development of a validated method to identify genomic regions with novel families of oriTs across bacterial plasmids.

中文翻译：

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一种检测质粒偶联转移序列起点的方法


质粒偶联在过去几十年中得到了广泛的研究。然而，在大多数质粒中，偶联所需的最小区域（转移起点 （oriT） 序列）是未知的。已知 oriT 的表征使开发一种经过验证的方法能够识别细菌质粒中具有新 oriT 家族的基因组区域。