A study shows that senescence induced in the liver can spread systemically to precipitate multi-organ dysfunction. The work identifies TGFβ signalling as a key mediator of this transmission, suggesting therapeutic avenues to prevent multi-organ failure in severe liver diseases.

中文翻译：

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对肝脏衰老的全身性影响


一项研究表明，肝脏中诱导的衰老可以全身扩散，从而诱发多器官功能障碍。该工作确定 TGFβ 信号是这种传递的关键介质，提出了预防严重肝病多器官衰竭的治疗途径。