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Tocilizumab for Advanced Non-Small-Cell Lung Cancer With Concomitant Cachexia: An Observational Study
Journal of Cachexia, Sarcopenia and Muscle ( IF 9.4 ) Pub Date : 2024-11-11 , DOI: 10.1002/jcsm.13638
Yang Du, Xiao-Yan Liu, Rui-Li Pan, Xiao-Tong Zhang, Xiao-Yan Si, Min-Jiang Chen, Meng-Zhao Wang, Li Zhang

Cancer cachexia significantly contributes to morbidity and mortality in patients with non-small-cell lung cancer (NSCLC). Inflammatory pathways mediated by interleukin-6 (IL-6) play a crucial role in the development of cancer cachexia. This study aimed to investigate the use of tocilizumab in the management of NSCLC with coexisting IL-6-elevated cachexia.

中文翻译:


托珠单抗治疗伴有恶病质的晚期非小细胞肺癌:一项观察性研究



癌症恶病质显著增加非小细胞肺癌 (NSCLC) 患者的发病率和死亡率。白细胞介素 6 (IL-6) 介导的炎症通路在癌症恶病质的发展中起着至关重要的作用。本研究旨在探讨托珠单抗在合并 IL-6 升高恶病质的 NSCLC 治疗中的应用。
更新日期:2024-11-11
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