当前位置: X-MOL 学术Signal Transduct. Target Ther. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Post-fast refeeding: rise of intestinal stemness and mutagen-induced cancer risk through polyamine metabolism
Signal Transduction and Targeted Therapy ( IF 40.8 ) Pub Date : 2024-11-11 , DOI: 10.1038/s41392-024-02038-1
Sarah Brunner, Klaus-Peter Janssen, Josef Ecker

An increased intestinal stem cell activity following post fast-refeeding is beneficial for regeneration, but too much could increase the risk for cancer in mice, as reported in a recent study by Imada and colleagues published in Nature.1 In consequence, fast-refeeding cycles should be thoroughly planned, when dietary strategies are considered for regeneration to minimize cancer risks.



中文翻译:


禁食后再喂养:肠道干性增加和诱变剂通过多胺代谢诱导的癌症风险



正如 Imada 及其同事最近发表在《自然》杂志上的一项研究中所报道的那样,禁食后肠道干细胞活性增加后肠道干细胞活性增加有利于再生,但过多会增加小鼠患癌症的风险。1 因此,当考虑饮食策略进行再生以最大限度地降低癌症风险时,应彻底规划快速再喂养周期。

更新日期:2024-11-12
down
wechat
bug