Behavioural symptoms are common manifestations of Parkinson’s disease (PD). Early behavioural symptoms characterise mild behavioural impairment (MBI). The prevalence and intensity of MBI in people with PD (PwP) have been studied across various cohorts. However, methodological differences have obscured our understanding of MBI in these individuals. This systematic review examines and synthesises findings from relevant studies, enhancing understanding of the symptoms and implications of MBI in PD. Nine studies from five separate research institutions were identified. The conceptualisation of MBI varied considerably, affecting the reported prevalence rates of MBI in individuals with early-stage PD. Among PwP, MBI was associated higher education and impaired cognition. Affective dysregulation and impulse control disorders were primary contributors to MBI; abnormal perception was least contributor. This systematic review underscores the specific characteristics and incidence of MBI in early-stage PD. Mood and impulse control disorders are primary concerns associated with MBI. Future longitudinal studies are required to clarify the progression of these symptoms and evaluate MBI’s potential as an indicator for PD-related dementia or increased dependency.

中文翻译：

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帕金森病的轻度行为障碍：系统评价


行为症状是帕金森病 （PD） 的常见表现。早期行为症状是轻度行为障碍 （mild behavioural impairment， MBI） 的特征。已在各个队列中研究了 PD 患者 （PwP） 中 MBI 的患病率和强度。然而，方法学的差异掩盖了我们对这些个体 MBI 的理解。本系统综述检查和综合了相关研究的结果，增强了对 PD 中 MBI 症状和影响的理解。确定了来自 5 个独立研究机构的 9 项研究。MBI 的概念化差异很大，影响了早期 PD 个体中报告的 MBI 患病率。在 PwP 中，MBI 与高等教育和认知障碍相关。情感失调和冲动控制障碍是 MBI 的主要因素;异常感知的贡献最小。本系统评价强调了 MBI 在早期 PD 中的具体特征和发生率。情绪和冲动控制障碍是与 MBI 相关的主要问题。需要未来的纵向研究来阐明这些症状的进展，并评估 MBI 作为 PD 相关痴呆或依赖性增加指标的潜力。