Antipsychotic medications targeting dopamine receptors were identified 70 years ago. Recent clinical trials have shown that agonists of muscarinic acetylcholinergic receptors can improve both psychotic and negative symptoms in schizophrenia. Here, this new approach to the treatment of schizophrenia is reviewed in anticipation of the drugs being licensed clinically.

中文翻译：

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精神分裂症 – 即将推出新的治疗方法

70 年前就发现了针对多巴胺受体的抗精神病药物。最近的临床试验表明，毒蕈碱乙酰胆碱能受体的激动剂可以改善精神分裂症的精神病和阴性症状。在这里，对这种治疗精神分裂症的新方法进行了审查，以期这些药物获得临床许可。