A gold(I)-catalyzed regioselective cycloisomerization of bis(indol-3-yl)-ynamides for the rapid construction of five-membered ring linked bisindole derivatives has been reported, affording the desired products in the range of 72%–94% yields under mild conditions along with broad substrate scope. Moreover, DFT calculation of the NBO (natural bond orbital) charge supports the origin of its regioselectivity.

中文翻译：

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金（I） 催化的双（吲哚-3-基）-ynami 的区域选择性环异构化以获得五元环连接的双辛哚衍生物

据报道，金 （I） 催化的双（吲哚-3-基）-ynami 区域选择性环异构化用于快速构建五元环连接的双吲哚衍生物，在温和条件下提供 72%–94% 产率范围内的理想产物以及广泛的底物范围。此外，NBO（天然键轨道）电荷的 DFT 计算支持其区域选择性的来源。