A gold(I)‐catalyzed regioselective cycloisomerization of bis(indol‐3‐yl)‐ynamides for the rapid construction of five‐membered ring linked bisindole derivatives has been reported, affording the desired products in the range of 72% ‐ 94% yields under mild conditions along with broad substrate scope. Moreover, DFT calculation of the NBO (natural bond orbital) charge supports the origin of its regioselectivity.

中文翻译：

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金（I）催化的双（吲哚-3-基）-亚胺的区域选择性环异构化以获得五元环连接的双辛哚衍生物


据报道，双（吲哚-3-基）-亚胺的区域选择性环异构化用于快速构建五元环连接的双吲哚衍生物，在温和的条件下提供 72% ‐ 94% 收率的所需产物以及广泛的底物范围。此外，NBO（天然键轨道）电荷的 DFT 计算支持其区域选择性的来源。