The enzymatically regioselective catalyzed incorporation of cysteine sulfoxide into histidine generates physiologically important antioxidants such as ergothioneine and ovothiol. In this issue of Structure, Ireland et al.1 report the crystal structure of EgtB-IV, which provides insights into the convergent evolution of sulfoxide synthase.

中文翻译：

---

EgtB-IV 结构中留下的趋同进化痕迹


半胱氨酸亚砜在酶促区域选择性催化下掺入组氨酸中，产生生理上重要的抗氧化剂，如麦角硫因和卵硫醇。在本期 Structure中，Ireland et al.1 报道了 EgtB-IV 的晶体结构，为亚砜合酶的趋同进化提供了见解。