We successfully found that boroxazolidone can dissociate under aqueous conditions, which were applicable to a solution containing proteins. The immobilization of a newly synthesized diarylborinic acid on beads enabled the capture and release of target proteins of bioactive compounds through boroxazolidone formation and dissociation.

中文翻译：

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温和的硼沙唑酮形成和解离：在生物活性分子靶点鉴定中的应用


我们成功发现硼唑酮可以在水性条件下解离，这适用于含有蛋白质的溶液。将新合成的二芳基硼酸固定在磁珠上，能够通过硼唑唑酮的形成和解离捕获和释放生物活性化合物的靶蛋白。