Near‐infrared mechanoluminescent (NIR ML) materials have attracted attention due to their advantages, such as in situ and real‐time monitoring of biomechanical information in vivo. However, most ML materials are focused on the UV–vis light range, which limits their potential applications in the biological field. In this work, a broadband NIR ML material Ca2YGa3Ge2O12: 0.10Cr3+ (CYGGG: 0.10Cr3+) is successfully prepared by chemical co‐substitution and Cr3+ heavy doping. Density functional theory (DFT) calculations are used to determine the type of defects in the material, and the composite defects formed by interstitial oxygen (iO′′) and antisite defects (CaY′ ‐ YCa°) mostly dominate NIR ML. Cr3+ ions act as electronic bridges to regulate energy levels, becoming the key to turning on the Nd3+ ion's NIR ML. Finally, based on the excellent ML properties of CYGGG: 0.10Cr3+ and CYGGG: 0.10Cr3+, 0.01Nd3+, the ML composites can penetrate pork tissues of different compositions/thicknesses under stress loads. Potentially, this work tries to realize biological tissue stress imaging, providing a new way for the biological application of NIR ML materials.

中文翻译：

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通过能量级工程调控宽带近红外机械发光，用于潜在的生物力学成像


近红外机械发光 （NIR ML） 材料因其优点而受到关注，例如原位和实时监测体内生物力学信息。然而，大多数 ML 材料都集中在紫外-可见光范围内，这限制了它们在生物领域的潜在应用。在本工作中，通过化学共取代和 Cr3+ 重掺杂成功制备了宽带近红外 ML 材料 Ca2YGa3G2O12：0.10Cr3+ （CYGGG： 0.10Cr3+）。密度泛函理论 （DFT） 计算用于确定材料中缺陷的类型，由间隙氧 （iO′′） 和反位缺陷 （CaY′ ‐ YCa°） 形成的复合缺陷主要在 NIR ML 中占主导地位。Cr3+ 离子充当调节能级的电子桥，成为打开 Nd3+ 离子的 NIR ML 的关键。最后，基于 CYGGG：0.10Cr3+ 和 CYGGG：0.10Cr3+、0.01Nd3+ 的优异 ML 性能，ML 复合材料可以在应力载荷下穿透不同成分/厚度的猪组织。这项工作可能试图实现生物组织应力成像，为 NIR ML 材料的生物学应用提供一条新途径。