An inappropriate induction of trained immunity in the bone marrow progenitors of immune cells has been described to underlie chronic inflammatory processes. Mills and colleagues’ recently published paper in Cell Stem Cell shows that maladaptive trained immunity drives inflammation in autoimmune processes,¹ opening a new area of research in autoimmunity.

中文翻译：

---

骨髓中训练有素的免疫力：自身免疫的枢纽


免疫细胞的骨髓祖细胞中训练有素的免疫力的不适当诱导已被证明是慢性炎症过程的基础。Mills 及其同事最近在 Cell Stem Cell 上发表的论文表明，适应不良的训练有素的免疫会驱动自身免疫过程中的炎症，¹ 开辟了自身免疫的新研究领域。