Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a protein-coated, single-stranded RNA virus that parasitizes and infects primates, including humans. The current detection methods are mainly carried out using humans as a medium, such as a chest computed tomography (CT) examination, nucleic acid detection, antibody detection, and antigen detection. In addition, SARS-CoV-2 in bioaerosols is an important way of transmission and infection, which has attracted wide attention. In this paper, we simulate a sampling system of SARS-CoV-2 in bioaerosols and detect SARS-CoV-2 in bioaerosols by means of a magnetoelastic (ME) sensing device based on an Android intelligent terminal, which can directly detect SARS-CoV-2 in bioaerosols in a certain unit environment. This approach aims to achieve early detection and prevention. The experimental results show that the sampling system can successfully collect SARS-CoV-2 in bioaerosols. In the linear range of 5–20 ng/mL, the ME sensing detection system results closely match those of the calibration instrument (VNA), with goodness-of-fit values of 0.997 and 0.995, respectively. This work demonstrates that the ME sensing detection system proposed is stable, highly specific, real-time, rapid, and has certain reference values and feasibility.

中文翻译：

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用于快速检测生物气溶胶中 SARS-CoV-2 的磁弹性免疫传感器


严重急性呼吸系统综合症冠状病毒 2 （SARS-CoV-2） 是一种蛋白质包被的单链 RNA 病毒，可寄生并感染包括人类在内的灵长类动物。目前的检测方法主要以人类为媒介进行，如胸部计算机断层扫描 （CT） 检查、核酸检测、抗体检测和抗原检测。此外，生物气溶胶中的 SARS-CoV-2 是一种重要的传播和感染方式，引起了广泛关注。在本文中，我们模拟了生物气溶胶中 SARS-CoV-2 的采样系统，并通过基于 Android 智能终端的磁弹性 （ME） 传感设备检测生物气溶胶中的 SARS-CoV-2，该设备可以直接检测特定单元环境中生物气溶胶中的 SARS-CoV-2。这种方法旨在实现早期发现和预防。实验结果表明，该采样系统可以成功采集生物气溶胶中的 SARS-CoV-2。在 5–20 ng/mL 的线性范围内，ME 传感检测系统的结果与校准仪器 （VNA） 的结果非常匹配，拟合优度值分别为 0.997 和 0.995。本工作表明，所提出的 ME 传感检测系统稳定、特异性高、实时性、快速性，具有一定的参考价值和可行性。