Recent advancements in science and technology have significantly enhanced public health by integrating novel materials and early diagnostic methods. A key focus is on MXenes, a class of materials known for their distinctive morphology and exceptional stability in diverse environments. MXenes possess notable structural engineering capabilities, enabling their design and synthesis into various forms tailored for specific applications. Their surface can be functionalized with different groups to enable chemical binding and physical attachment to various molecules, while variations in layer thickness and elemental composition influence their electrical conductivity and stability. This perspective article examines recent structural innovations in MXenes, particularly their application in biosensors. We highlight the role of aptamer surface decorations, which offer specific and selective binding for detecting a broad spectrum of analytes, thus underscoring MXenes’ potential in advancing diagnostic technologies and improving public health.

中文翻译：

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基于 MXene 的 aptasensor：对最新进展的看法


最近的科学和技术进步通过整合新材料和早期诊断方法显着改善了公共卫生。一个重点是 MXenes，这类材料以其独特的形态和在不同环境中的出色稳定性而闻名。MXenes 具有显著的结构工程能力，能够将其设计和合成为针对特定应用量身定制的各种形式。它们的表面可以用不同的基团进行功能化，以实现化学结合和物理附着到各种分子上，而层厚和元素组成的变化会影响它们的导电性和稳定性。这篇透视文章研究了 MXenes 的最新结构创新，特别是它们在生物传感器中的应用。我们强调了适配体表面装饰的作用，它为检测广泛的分析物提供特异性和选择性结合，从而强调了 MXenes 在推进诊断技术和改善公共卫生方面的潜力。