With the continuous application of new agricultural chemicals in agricultural systems, it is imperative to study the environmental fate and potential transformation products (TPs) of these chemicals to better assess their ecological and health risks, as well as guide scientific application. The dissipation of fluchloraminopyr was firstly evaluated under aerobic/anaerobic condition in four representative soils, with Dissipation Time 50 (DT₅₀) values ranging from 0.107 to 4.76 days. Eight TPs generated by soil degradation were identified via Ultra-High Performance Liquid Chromatography coupled with Quadrupole Time-of-Flight Mass Spectrometry (UHPLC-QTOF/MS) and Density Functional Theory (DFT) calculations. The predominant transformation reactions of fluchloraminopyr in soil include oxidation, dechlorination, hydroxylation, and acetylation. The predictions from toxicological software indicated that the acute and chronic toxicity of TPs to aquatic organisms was significantly lower than that of fluchloraminopyr. Moreover, both M267 and M221 exhibited higher acute oral toxicity to terrestrial organisms compared to the parent compound. Consequently, these findings offer essential ecological risk evaluation data for the judicious application of fluchloraminopyr.

中文翻译：

---

新型除草剂氟氯胺吡啶在土壤中的降解：消散动力学、降解途径、转化产物鉴定和生态毒性评价


随着新型农用化学品在农业系统中的不断应用，研究这些化学品的环境归宿和潜在的转化产物 （TPs） 以更好地评估其生态和健康风险，并指导科学应用。首先在 4 种代表性土壤中用氧/厌氧条件下评价氟氯胺吡啶的消散情况，消散时间 50 （DT₅₀） 值范围为 0.107 至 4.76 天。通过超高效液相色谱-四极杆飞行时间质谱 （UHPLC-QTOF/MS） 和密度泛函理论 （DFT） 计算鉴定了土壤降解产生的 8 种 TPs。氟氯胺吡嘧在土壤中的主要转化反应包括氧化、脱氯、羟基化和乙酰化。毒理学软件的预测表明，TPs 对水生生物的急性和慢性毒性显著低于氟氯胺吡啶。此外，与母体化合物相比，M267 和 M221 对陆生生物表现出更高的急性口服毒性。因此，这些发现为氟氯胺吡啶的明智应用提供了重要的生态风险评估数据。