Engel et al. conducted a genetic screen in which they identified the Fanconi anaemia (FA) pathway as a driver of chromothripsis, complex genomic rearrangements and generation of extrachromosomal DNA.

中文翻译：

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Fanconi 贫血通路诱导染色体破碎


Engel 等人进行了一项遗传筛选，他们确定了 Fanconi 贫血 （FA） 通路是染色体脱血、复杂基因组重排和染色体外 DNA 生成的驱动因素。