In recent decades, the prevalence of obesity has increased significantly, leading to an epidemic at the global level. Obesity is associated with various metabolic alterations and increases the risk of cardiovascular disease. The most devastating manifestation of cardiovascular disease is sudden cardiac death (SCD), leading to substantial years of potential life lost worldwide. Obesity-related SCD is an increasingly important public health problem and warrants a specific investigative focus on improved risk stratification and prevention. In this review, we summarize the current evidence regarding management of SCD in obesity and discuss knowledge gaps as well as future directions in this field.

中文翻译：

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肥胖猝死：机制和管理


近几十年来，肥胖症的患病率显著增加，导致全球流行病。肥胖与各种代谢改变有关，并增加患心血管疾病的风险。心血管疾病最具破坏性的表现是心源性猝死 （SCD），导致全球范围内可能损失大量生命。与肥胖相关的 SCD 是一个日益重要的公共卫生问题，需要特别关注改进风险分层和预防。在本综述中，我们总结了有关肥胖 SCD 管理的当前证据，并讨论了该领域的知识差距和未来方向。