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Anti-integrin αvβ6 Autoantibodies are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-10-25 , DOI: 10.1016/j.cgh.2024.10.005 Hannah Bloemen, Alexandra E. Livanos, Adrielly Martins, Richard Dean, Ana Catarina Bravo, Arno R. Bourgonje, Michael Tankelevich, Jake Herb, Judy Cho, André Anastácio Santos, Cecília M.P. Rodrigues, Francesca Petralia, Jean-Frederic Colombel, Christopher L. Bowlus, Thomas Schiano, Joana Torres, Cynthia Levy, Saurabh Mehandru
Clinical Gastroenterology and Hepatology ( IF 11.6 ) Pub Date : 2024-10-25 , DOI: 10.1016/j.cgh.2024.10.005 Hannah Bloemen, Alexandra E. Livanos, Adrielly Martins, Richard Dean, Ana Catarina Bravo, Arno R. Bourgonje, Michael Tankelevich, Jake Herb, Judy Cho, André Anastácio Santos, Cecília M.P. Rodrigues, Francesca Petralia, Jean-Frederic Colombel, Christopher L. Bowlus, Thomas Schiano, Joana Torres, Cynthia Levy, Saurabh Mehandru
Anti-integrin αvβ6 autoantibodies (anti-αvβ6) are found in more than 50% of individuals with ulcerative colitis (UC). We aimed to determine the prevalence of anti-αvβ6 in patients with primary sclerosing cholangitis (PSC) and their association with liver disease severity.
中文翻译：
抗整合素 αvβ6 自身抗体在伴有炎症性肠病的原发性硬化性胆管炎患者中增加，并与肝病严重程度相关
抗整合素 αvβ6 自身抗体 （anti-αvβ6） 存在于超过 50% 的溃疡性结肠炎 （UC） 患者中。我们旨在确定原发性硬化性胆管炎 （PSC） 患者抗 αvβ6 的患病率及其与肝病严重程度的关系。
更新日期：2024-10-25
中文翻译：
抗整合素 αvβ6 自身抗体在伴有炎症性肠病的原发性硬化性胆管炎患者中增加，并与肝病严重程度相关
抗整合素 αvβ6 自身抗体 （anti-αvβ6） 存在于超过 50% 的溃疡性结肠炎 （UC） 患者中。我们旨在确定原发性硬化性胆管炎 （PSC） 患者抗 αvβ6 的患病率及其与肝病严重程度的关系。
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