The direct functionalization of remote C(sp³)–H is valuable but challenging, and is even more difficult to achieve than the γ-C(sp³)–H functionalization of alcohols. Among the strategies, hydrogen atom transfer (HAT) is one of the solutions for such transformations. Herein, we designed a migration reaction involving carbon monoxide, forming an alkoxy radical by photocatalysis, and used carbon monoxide to extend the carbon chain to provide a site for the migration of heteroaryl groups, which makes 1,4-HAT more advantageous, and we relied on this strategy to successfully achieve the synthesis of 1,4-dicarbonyl compounds by γ-C(sp³) functionalization of alcohols.

中文翻译：

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CO 插入使 γ-C（sp3）–H 杂芳基羰基化通过杂芳基迁移实现叔醇的


远程 C（sp³）-H 的直接官能化很有价值但具有挑战性，并且比醇的 γ-C（sp³）-H 官能团化更难实现。在这些策略中，氢原子转移 （HAT） 是此类转变的解决方案之一。在此，我们设计了一种涉及一氧化碳的迁移反应，通过光催化形成烷氧基自由基，并利用一氧化碳延伸碳链，为杂芳基的迁移提供位点，这使得 1,4-HAT 更具优势，我们依靠这种策略成功地实现了醇的 γ-C（sp³） 官能化合成 1,4-二羰基化合物。