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Diabetes, IL-10 and the brain’s microvascular crisis
Nature Metabolism ( IF 18.9 ) Pub Date : 2024-11-04 , DOI: 10.1038/s42255-024-01161-1 Celine E. Riera
Nature Metabolism ( IF 18.9 ) Pub Date : 2024-11-04 , DOI: 10.1038/s42255-024-01161-1 Celine E. Riera
A new study finds that capillary vessels become obstructed in diabetes and that their dysfunction may cause microvascular damage and lead to cognitive deficits. Such obstruction is independent of the elevated blood sugar found in diabetes and is triggered by elevated interleukin-10 cytokine signalling in cerebral blood vessel endothelial cells.
中文翻译:
糖尿病、IL-10 和大脑的微血管危象
一项新的研究发现,糖尿病患者的毛细血管会阻塞,其功能障碍可能导致微血管损伤并导致认知缺陷。这种阻塞与糖尿病中发现的血糖升高无关,并且是由脑血管内皮细胞中白细胞介素 10 细胞因子信号升高触发的。
更新日期:2024-11-04
中文翻译:
糖尿病、IL-10 和大脑的微血管危象
一项新的研究发现,糖尿病患者的毛细血管会阻塞,其功能障碍可能导致微血管损伤并导致认知缺陷。这种阻塞与糖尿病中发现的血糖升高无关,并且是由脑血管内皮细胞中白细胞介素 10 细胞因子信号升高触发的。